High Triglycerides: Fasting Blood Lipid Profile
The purpose of this website is to present, to all who want the knowledge, a safe and dependable method through which individuals can lower their elevated blood triglyceride levels. You can achieve astonishing results - if you put your mind to it.
The blood tests make available to the physician a great amount of information about a patient's physical condition at the time of the testing. After review and interpretation, the blood test results play an important part in an overall medical diagnosis.
Most reference ranges - often referred to as 'normal' ranges - are typically defined as the range of values of the median 95 percent of the healthy population; therefore, it is unlikely that a given blood sample, even from a healthy patient, will show "normal" values for every blood test taken.
For this reason, caution should be exercised by examining physicians to prevent overreaction to mild abnormalities without the interpretation of those test results.
Blood lipid test, mainly cholesterol and triglycerides, is a screening test which is used to try to detect a disease when there is little or no evidence that a person has a suspected disease.
Therefore, measuring lipid levels helps to identify one of the risks of heart disease in those who may show no symptoms of heart disease. Blood lipid test then is a tool for the physician to detect a potentially harmful and evolving condition.
However, sometimes a test result may be:
Because your physician cannot always be sure whether or not the reported result of a particular test from a particular person is false or true, a person with an abnormal result may often need to be re-tested or undergo a different type of testing.
"Normal" test result values, expressed as a reference range, vary somewhat among laboratories, due to methodology and even geography.
Also tests and testing vary widely in different parts of the world, and in different parts of most countries, mainly due to characteristics in the population, among other factors.
In assessing the risk of heart disease, standard medicine targets usually total cholesterol and LDL-"bad" cholesterol levels. However, people with high cholesterol often have high triglycerides, especially when there is no another disorder present.
Therefore, the type of standard treatment used to lower cholesterol
American blood laboratories use a different version of the metric system than does most of the rest of the world, which uses the SI or Systeme Internationale d’Units.
The SI is an international standard recognized around the world – except by the United States of America, Liberia, and Myanmar (Burma) who will probably adopt it in due time.
In some cases translation between the two systems is easy, but the difference between the two is most pronounced in the measurement of chemical concentration.
The American System: mg/dL
The term "mg/dL" then is the abbreviation for milligrams (mg) per deciliter (dL) and describes how much lipid is present in a specific amount of blood.
A deciliter is 1/10 of a liter or about 1/4 of a pint.
The SI System: mmol/L
The term "mmol/L" is the abbreviation for millimoles (mmol) per liter/litre (L) and describes how much lipid is present in a specific amount of blood.
A millimole is 1/1,000 of a mole. A mole is an amount of a substance (in this case, triglyceride or cholesterol) that contains a certain number of molecules or atoms.
Since mass per mole varies with the molecular weight of the substance being analyzed, conversion between the American and SI units requires many different conversion factors.
Glucose (GLU) Conversion:
The published evidence is quite clear in documenting that the actual cholesterol level itself is not the most important risk factor of cardiovascular disease. It is the ratio between the level of HDL-good cholesterol and total cholesterol.
HDL-"good" cholesterol/total cholesterol ratio:
Triglyceride/HDL-"good" cholesterol ratio:
Routine screening consists of measurement of total cholesterol and HDL. Blood drawn after an overnight fast will allow accurate measurement of VLDL and triglycerides in addition to the total cholesterol and HDL.
However, the ultracentrifugal measurement of LDL-cholesterol is time consuming and expensive, and requires specialist equipment. For this reason, LDL-cholesterol is most commonly estimated from quantitative measurements of total and HDL-cholesterol and plasma triglycerides (TG) using the empirical relationship of Friedewald et al.(1972):
PLEASE NOTE: If LDL-cholesterol is calculated using all concentrations in mg/dL then the equation is as follows:
The quotient ([TG]/5) is used as an estimate of VLDL-cholesterol concentration. It assumes,
Neither assumption is strictly true.
The Friedewald equation for calculating LDL-cholesterol is generally unreliable (and should not be used) under the following circumstances: when
PLEASE NOTE: In situations (1) and (2), a reliable LDL-cholesterol may be obtained using the direct LDL-cholesterol test. In situation (3), ultracentrifugation is required to confirm the atherogenic and distinctly treatable Type III disorder and to obtain a reliable LDL-cholesterol.
William E. Feeman Jr. MD, a family practitioner, Bowling Green, Ohio, United States, conducted the long-term, observational Bowling Green Study, which has followed 2,818 family-medicine patients since 1974.
The effort of this investigator-initiated and self-funded study was to determine what components of lipid profiles have the greatest impact on risk of atherosclerotic events.
In his scientific poster, Dr. Freeman presented data on 1,339 men and 1,479 women ages less than 29 to greater than age 80 who were seen in his practice between 1974 and 2001.
According to Dr. Freeman's findings, the earliest onset of atherosclerosis have people with abnormal values for
This group does require aggressive lipid therapy.
The most typical lipid disorder, however, represent people with
The definition of metabolic syndrome X or insulin resistance represent people with
All these people require lipid therapy as - according to Dr. Freeman - dyslipidemia, after smoking, is the next most important risk factor for atherosclerosis.
However, lipid therapy is not required in people with
The first important step in choosing medical treatment for hypertriglyceridemia is to consider a patient's risk profile. Usually, the major cardiovascular risk factors are associated with:
Here are standard treatment options offered at a typical doctor's office:
1. High Triglycerides and Low HDL-"Good" Cholesterol:
Research suggests that the combination of low HDL and high triglycerides indicates a generalized disorder of lipid (fat) metabolism, called metabolic syndrome X, which may place you at high cardiovascular risk.
In this case, before prescribing any medication, your doctor will recommend for three intial months basic lifestyle changes - suitable for all people with elevated triglycerides and other lipids - such as:
Not Responding to Lifestyle Changes:
From doctors' point of view, being on medication doesn’t mean you failed – just that you need a little more help that diet and exercise can provide. However, you would be astounded how many people would rather take a pill than consider changing anything else.
You need to take your medication for initially 3 months and then check your triglycerides level under medical supervision.
2. Familial Hyperlipidemia:
Not Responding to Niacin:
Without treatment you may eventually develop atherosclerosis leading to a heart attack. (Familial combined hyperlipidemia manifests as high cholesterol, high triglycerides, or both).
3. Triglycerides Over 500 mg/dL:
If left untreated, triglycerides over 500 mg/dL can cause pancreatitis (the inflammation of pancreas).
4. Borderline-High Triglycerides and Normal LDL-"Bad" Cholesterol:
Not all doctors would agree you should be treated medically, unless you have history of vascular disease. However, this line of treatment may be considered, if you
5. High Triglycerides and High LDL-"Bad" Cholesterol:
Not Responding to Statin Therapy:
High triglycerides may be caused by other disorders, such as type 2 diabetes, alcoholism, hypothyroidism, Cushing’s syndrome, liver disease, uremia, dysglobulinemia, or nephrotic syndrome.
PLEASE NOTE: Because drinking can cause hypertriglyceridemia, you will be asked by your doctor about your drinking paterns, and suggested - if needed - to cut back or eliminate alcohol before exploring other treatment options.
Our customers write to us:
Thanks! I have been trying to reduce my triglycerides for several years now. I was placed on (...) Tricor which produced side effects so badly that I could not take it.
I started taking your Triglycerides Reduction Formula and following the Diet just under two months ago.
My doctor just called and gave me my lab results. My triglycerides fell from 432 to 170, my HDL went from 30 to 48 and all the other results were normal which hasn't happened in years.
Needless to say, I just ordered another 2 months' supply of your Triglycerides Reduction Formula.
It really works!
A study in the Archives of Neurology published unsettling new information: "Atorvastatin decreases the Coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke" (Arch Neurol, Jun 2004; 61: 889 - 89).
Atorvastatin is the chemical name for Lipitor ®, the world’s best selling cholesterol-lowering prescription drug.
This new study, however, is simply confirmation of what scientists have known for some time: “miracle” but potentially harmful statin drugs may lower levels of Coenzyme Q10 (CoQ10) - a superior antioxidant, essential for the production of energy in every cell of the body.
Isn’t it a little ironic? Millions of heart patients are taking a drug that depletes CoQ10 which - through many years of research - has been shown to be effective in protecting the cardiovascular system and helping to prevent heart disease.
Meanwhile, the United Kingdom has decided to reclassify Zocor (another best selling statin drug) as over-the-counter (OTC), in spite of the fact that Zocor may cause muscle pain or weakness, as well as liver problems (according to the Zocor website).
PLEASE NOTE: If you are on statins, taking 100 mg of CoQ10 daily will help you replenish depleted CoQ10 stores as you work with your doctor in weaning yourself off these drugs.
Coenzyme Q10 is one of the most valuable investments you can make for your heart - and one of the most important nutrients you can take for your health. In fact, if you can only take one or two supplements a day - CoQ10 should absolutely be one of them!
Lipid measurement may show normal total cholesterol, with a low HDL-“good” cholesterol and a moderately elevated triglyceride level; for example, total cholesterol of 197 mg/dL, an LDL-“bad” of 120 mg/dL, an HDL of 35 mg/dL, and a triglyceride of 210 mg/dL. That pattern is not unusual; in fact, it is seen in about 20 percent to 30 percent of people who have had a myocardial infarction (heart attack).
However, an important issue is how to best manage these people.
In those cases, doctors may now use a new commercially available test. This procedure uses nuclear magnetic resonance (NMR) spectroscopy to fractionate VLDL, LDL, and HDL concentrations into 15 different subfractions. It is completely automated and takes only about one minute to perform, since it measures all subfractions simultaneously.
For example, two people may have similar lipid levels, but if NMR spectroscopy shows that one has a much higher proportion of small, dense lipoprotein particles, that might tip the balance toward treatment, especially if there is a family history of cardiovascular artery disease (CAD) or other risk factors.
Monday - Friday: 10:00 am - 3:00 pm EST (Weekends & Holidays Excluded)